Zocon T Kit 1’s

INTRODUCTION

ZOCON T KIT is a combination of Fluconazole and Tinidazole which belongs to the group of medicines called Antifungal and Antiprotozoal agents respectively. It is used to treat vaginal infections caused by fungus.

Avoid alcohol consumption while taking this medicine because it may cause abdominal cramps, nausea, vomiting, headache, flushing and tachycardia.

Before taking ZOCON T KIT inform your doctor if you have lung, liver or kidney disease or heart rhythm disorders.

ZOCON T KIT is generally not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking.

ZOCON T KIT is not recommended for use in breast feeding women as it may pass through the breast milk. Contact your doctor before taking.

ZOCON T KIT is not recommended for use in children. Contact your doctor before taking. ZOCON T KIT should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking.

The most common side effects of this medicine are nausea, vomiting, headache, stomach discomfort, indigestion, diarrhoea, constipation, anorexia, change in taste, rashes, dizziness, weakness etc. Contact your doctor if any of the side effects worsen.

USES OF ZOCON T KIT
Used to treat vaginal infections
HOW ZOCON T KIT WORKS

ZOCON T KIT helps to treat vaginal infections, where Fluconazole works by inhibiting the formation of ergosterol which is essential for fungal cell wall synthesis, leading to death of fungal cells and Tinidazole works by damaging the DNA. Together, reduces the infection.

DIRECTIONS FOR USE

Take this medicine as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the right dose depends on your age, body weight and disease condition.

SIDE EFFECTS OF ZOCON T KIT
COMMON
Nausea, vomiting
Headache
Stomach discomfort
Indigestion
Diarrhoea
Constipation
Anorexia
Change in taste
Abnormal liver function tests
Rash
Dizziness
Weakness, fatigue or malaise
UNCOMMON
Pale skin, weakness or shortness of breath due to decrease in red blood cells
Inability to sleep, feeling drowsy
Fits
Dry mouth
Muscle pain
Fever, tiredness, feeling unwell
RARE
Decreased white blood cells and platelets
Reddish or purple skin discoloration
Low blood potassium levels
Elevated cholesterol levels
Shaking
Abnormal electrocardiogram (ECG), change in heart rate or rhythm
Hair loss

Stop taking the medicine and contact your doctor immediately if you experience any of the following side effects:

Skin rash, widespread blistering rash and skin peeling or red itchy spots on the skin, swelling of the face, eyelids, lips, tongue or throat causing sudden wheeziness, difficulty breathing or chest tightness and sores around the mouth, eyes, nose or genitals
DRESS (Drug Rash with Eosinophilia and Systemic symptoms) symptoms may include fever, swollen glands, widespread rash, increase in a type of white blood cell (eosinophilia) and inflammation of internal organs like liver, lungs, heart, kidneys and large intestine
Tiredness, loss of appetite, vomiting, yellowish discolouration of skin or whites of eye (jaundice) or liver failure
Signs of adrenal problems such as tiredness, muscle weakness, loss of appetite, weight loss, and abdominal pain
Abnormal vaginal bleeding or discharge
Vaginal or vulval sores, ulcers and blisters
Lower abdominal pain, burning on passing urine
HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if the symptom did not improve.

Nausea or Vomiting:

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for treating diarrhea. Contact your doctor if the symptom did not improve.

Indigestion:

Eat smaller meals but take frequently. Eat and exercise regularly. Contact your doctor if the symptom did not improve.

Constipation:

Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of water and exercise more regularly.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the symptom did not improve.

Stomach pain:

Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. Contact your doctor if the symptom did not improve.

WARNING & PRECAUTIONS
PREGNANCY

ZOCON T KIT is generally not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking.

BREASTFEEDING

ZOCON T KIT is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you have dizziness, fits (convulsions), after taking [GBNEYWORD].

ALCOHOL

Avoid alcohol consumption while taking this medicine because it may cause abdominal cramps, nausea, vomiting, headache.

KIDNEY

ZOCON T KIT should be used caution in patients with kidney disease. Contact your doctor before taking.

LIVER

ZOCON T KIT should be used with caution in patients with liver disease. Contact your doctor before taking.

ALLERGY

Do not take ZOCON T KIT if you are allergic to Fluconazole, Tinidazole or other medicines used to treat yeast or fungal infections, or to lactose or some sugars or to other ingredients of this medicine.

LUNGS

ZOCON T KIT should be used with caution in patients with lung diseases like pneumonia. Contact your doctor before taking.

HEART DISEASE

ZOCON T KIT should be used caution in patients with heart rhythm disorders, heart failure. Contact your doctor before taking.

OTHERS

Before taking ZOCON T KIT, inform your doctor if you have:

Abnormal levels of potassium, calcium and magnesium in blood
Sexually transmitted disease
Fungal infection
Cryptococcal meningitis
Bone marrow transplantation
Urinary tract infections and peritonitis
Systemic Candida infections (Ex. candidemia, disseminated candidiasis)
Esophageal or oropharyngeal candidiasis
AIDS
Cancer
Diabetes
History of blood dyscrasias
Seizures
Peripheral neuropathy
Vertigo
Low immunity

Use in pediatrics:

ZOCON T KIT is not recommended for use in children. Contact your doctor before taking.

Use in geriatrics:

ZOCON T KIT should be used with caution in elderly patients (aged 65 years above). Contact your doctor before taking.

INTERACTIONS

A. Drug-Drug interactions:

Inform your physician, if you are taking,

Medicines used in allergies (terfenadine, astemizole)
Cisapride (medicines used to treat stomach upset)
Pimozide (medicines used in mental conditions)
Quinidine (medicines used to treat heart arrhythmia)
Erythromycin, azithromycin (medicines used to treat bacterial infections)
Medicines used to treat hypertension Ex. nifedipine, isradipine, amlodipine, felodipine and losartan
Rifampicin, rifampin, rifabutin (medicines used to treat infections like tuberculosis)
Medicines used to thin the blood or to prevent blood clots (Ex. warfarin)
Benzodiazepines (Ex. midazolam, triazolam) medicines used to treat insomnia and anxiety
Olaparib (medicines used to treat ovarian cancer)
Chlorpropamide, glibenclamide, glipizide or tolbutamide (medicines used to treat diabetes)
Phenytoin, phenobarbital, fosphenytoin carbamazepine (medicines used to treat fits)
Medicines used to prevent transplant rejection like cyclosporine, everolimus, sirolimus and tacrolimus
Theophylline (medicines used to treat asthma)
Tofacitinib (medicines used to treat rheumatoid arthritis)
Zidovudine, nevirapine, saquinavir (medicines used to treat HIV)
Ex. prednisone (medicines used to treat inflammation)
Oral contraceptives like levonorgestrel, ethinyl estradiol, norethindrone (medicines used to prevent pregnancy)
Alfentanil, fentanyl (medicines used in anaesthesia)
Celecoxib, parecoxib, flurbiprofen, naproxen, ibuprofen, lornoxicam, meloxicam, diclofenac (medicines used to treat pain)
Amitriptyline, nortriptyline (medicines used to treat depression)
Amphotericin B, voriconazole, ketoconazole (medicines used to treat fungal infections)
Cyclophosphamide and vinca alkaloids like vincristine, vinblastine (medicines used for cancer)
Halofantrine (medicines used to treat malaria)
Atorvastatin, simvastatin and fluvastatin (medicines used to treat high cholesterol levels)
Vitamin A (nutritional supplement)
Fentanyl or methadone (medicines used for severe pain)
Ivacaftor (medicines sued to treat cystic fibrosis)
Amiodarone (medicines used to treat uneven heartbeats or arrhythmias)
Hydrochlorothiazide
Cimetidine (medicines used for stomach ulcers)
Antacid (medicines used to treat indigestion, heartburn)
Tolbutamide, glipizide, nateglinide, and glyburide
Disulfiram (used for chronic alcoholism)
Lithium (medicines used to treat depression and mania)
Fluorouracil (medicines used to treat cancer)
Oxytetracycline (medicines used to treat bacterial infections)
Bosentan (medicines used to treat high blood pressure in lungs)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdosage are hallucinations and paranoid behaviour.

SYNOPSIS
Drug :   Fluconazole, Tinidazole
Pharmacological Category :   Antifungals, Anti protozoal
Therapeutic Indication :   Vaginal bacterial infections
Dosage Forms :   Tablet
MORE INFORMATION
Keep out of reach of children
Store ZOCON T KIT below 30°C
FAQs ABOUT ZOCON T KIT

How ZOCON T KIT work?

ZOCON T KIT helps to treat vaginal infections, where Fluconazole works by inhibiting the formation of ergosterol which is essential for fungal cell wall synthesis, leading to death of fungal cells and Tinidazole works by damaging the DNA. Together, reduces the infection.

What are the side effects of taking ZOCON T KIT?

The most common side effects of this medicine are nausea, vomiting, headache, stomach discomfort, indigestion, diarrhoea, constipation, anorexia, change in taste, rashes, abnormal liver function tests, fatigue or malaise, dizziness, weakness. Contact your doctor if any of the side effects worsen.

Can I use ZOCON T KIT in children?

No. ZOCON T KIT is not recommended for use in children. Contact your doctor before taking.

Does ZOCON T KIT cause fits?

Yes. ZOCON T KIT may cause fits. Contact your doctor, immediately if you experience any unusual symptoms like fits.

Can I use ZOCON T KIT while breast feeding?

No. ZOCON T KIT is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

Does ZOCON T KIT cause drowsiness?

Yes. ZOCON T KIT may cause drowsiness. Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the symptom did not improve.

REFERENCES

1. K.D.Tripathi. Anti-fungal drugs & Antifungal and other antiprotozoal drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page- 793,839.

2. Bethesda. Tinidazole. National Institute of Health. National Library of Medicine. National center for biotechnology information. Pubmed.gov. 2004. [Accessed on 7th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Tinidazole#section=Substances-by-Category

3. Sun Pharmaceutical Industries.  Electronic Medicines Compendium (EMC). [Revised on February 2021] [Accessed on 7th June 2022] https://www.medicines.org.uk/emc/files/pil.4438.pdf

4. Gedeon Richter Plc. Health Products Regulatory Authority (HPRA). [Revised on April 2018] [Accessed on 7th June 2022] http://www.hpra.ie/img/uploaded/swedocuments/2198529.PA1330_014_002.9d608f93-bc7b-4e4c-bd6f-14466eb52367.000001pil.180501.pdf

5. Zydus Pharmaceuticals USA Inc. Fluconazole. [Revised on March 2022] [Accessed on 7th June 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=69f199fa-bb92-4837-8b12-427a1c71f622

6. Pfizer. Tinidazole. [Revised on May 2019] [Accessed on 7th June 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=15227

7. Fluconazole. Mims.com. [Accessed on 7th June 2022] https://www.mims.com/india/drug/info/fluconazole?mtype=generic

8. Tinidazole. Mims.com. [Accessed on 7th June 2022] https://www.mims.com/india/drug/info/tinidazole?mtype=generic

USEFUL DIAGNOSTIC TESTS
Liver function test
Kidney function test
Complete blood count
Net Qty
1 N
Item Weight
20 g
Ingredient
Fluconazole 150MG+Tinidazole 1000MG
Hsn Code
30049039
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