TRAKLOT 500 Tablet 6’s

INTRODUCTION

TRAKLOT 500 TABLET contains Tranexamic Acid which belongs to theroup of medicines called Antifibrinolytics. It is used in the prevention and treatment of bleeding in conditions such as heavy menstrual bleeding in women, bleeding inside the digestive system (Ex. inflammatory bowel disease), bleeding from the nose, blood in urine (not caused by the kidney (renal parenchyma)), control bleeding after dental extraction in patients with coagulopathies and after cervix surgery.       

TRAKLOT 500 TABLET is not recommended for use in patients with blood clotting disorder or consumption coagulopathy, kidney disease, fits or seizure disorder, irregular menstrual cycle, acquired disturbances of color vision, venous or arterial thrombosis, active thromboembolic diseases such as deep vein thrombosis, pulmonary embolism and cerebral thrombosis, subarachnoid hemorrhage and blood in urine during periods.  

Before taking TRAKLOT 500 TABLET, inform your doctor if you had or have changes in normal bleeding pattern, family history of endometrial cancer, abnormal bleeding between periods, bleeding during or after sexual intercourse, premenstrual pain, lower abdominal pain, bleeding after menopause, are at risk of having a blood clot, diabetic, overweight, polycystic ovary syndrome (PCOS).   

TRAKLOT 500 TABLET should be used with caution in pregnant and breast-feeding women only if clearly advised by the doctor. Consult your doctor before taking TRAKLOT 500 TABLET. Your doctor may recommend you to take relevant tests to understand your existing condition.

Safety and effectiveness of TRAKLOT 500 TABLET in children and adolescents below 18 years of age has not been established yet and it is not recommended for use in elderly women after menopause (stoppage of periods).  

The most common side effects of taking TRAKLOT 500 TABLET are nausea, vomiting, diarrhea, headache, tiredness and stomach pain. Consult your doctor immediately if any of the side effect worsens.  

USES OF TRAKLOT 500 TABLET

It is used to treat and prevent bleeding in conditions such as:

Heavy menstrual bleeding in women
Bleeding from the nose
Bleeding inside the digestive system (gastrointestinal system, Ex. inflammatory bowel disease))  
Blood in urine (not caused by the kidney (renal parenchyma))
Bleeding after undergoing surgery (such as dental extraction in patients with coagulopathies, cervix surgery)  
HOW TRAKLOT 500 TABLET WORKS

TRAKLOT 500 TABLET prevents bleeding by blocking the plasminogen from binding with fibrin which results in bleeding. As a result, it prevents and controls bleeding associated with various conditions.

DIRECTIONS FOR USE

Take TRAKLOT 500 TABLET as directed by your physician. Swallow the medicine as a whole and do not crush or chew the medicine. Do not take this medicine before your period has started as it will not work properly. Your doctor will decide the correct dose, duration and frequency of TRAKLOT 500 TABLET for you depending upon age, weight and disease conditions.

SIDE EFFECTS OF TRAKLOT 500 TABLET
COMMON
Nausea, vomiting
Diarrhea, stomach pain
Headache
Sinus and nasal symptoms
Back, muscle or joint pain
Muscle cramps
Migraine
Anemia
Tiredness
UNCOMMON
Allergic skin reactions
RARE
Thromboembolic events (blood clot in vein)
Vision disturbances
Giddiness

Stop taking TRAKLOT 500 TABLET and contact your doctor immediately if you experience any of the following side effects:

Impaired vision (especially color), blood clot in the eye
Itchy, red or swollen skin
Serious blood clots
Pain or feelings of heaviness in the chest
Pain or swelling in the arms or legs
Sudden shortness of breath, fainting
Coughing up blood
HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.

Diarrhoea:

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptomets worse.    

Headache:

Drink ample amount of water and avoid skipping meals.et adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.   

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor. 

WARNING & PRECAUTIONS
PREGNANCY

TRAKLOT 500 TABLET should be used with caution in pregnant women only if considered clearly necessary. Inform your doctor immediately if you become pregnant or think you may be pregnant before using TRAKLOT 500 TABLET.

BREASTFEEDING

TRAKLOT 500 TABLET should be used with caution in breastfeeding women only if advised by the doctor as it may pass through the breast milk. Consult your doctor before taking TRAKLOT 500 TABLET.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you experience dizziness after taking TRAKLOT 500 TABLET.

KIDNEY

TRAKLOT 500 TABLET is not recommended for use in patients with severe kidney impairment.  TRAKLOT 500 TABLET should be used with caution in patients with mild to moderate kidney impairment and your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking TRAKLOT 500 TABLET.

LIVER

No dose adjustment is required in patients with hepatic impairment. Consult your doctor for advice.  

ALLERGY

Do not take TRAKLOT 500 TABLET if you are allergic to Tranexamic Acid or any other ingredients of this medicine.

LUNGS

TRAKLOT 500 TABLET is not recommended for use in patients with pulmonary embolism (arteries of the lungs are blocked by clot). Consult your doctor before taking TRAKLOT 500 TABLET.  

OTHERS

TRAKLOT 500 TABLET is not recommended for use if you:

Have a blood clotting disorder (consumption coagulopathy)
Have history of fits or seizure disorder
Have an irregular menstrual cycle
Have acquired disturbances of color vision
Have history of venous or arterial thrombosis (blood clot in artery/veins)
Have deep vein thrombosis, cerebral thrombosis (blood clot of cerebral vein in brain)
Have subarachnoid hemorrhage (bleeding in space between brain and tissue covering the brain)
Have blood in urine between periods

Before taking TRAKLOT 500 TABLET inform your physician if you:

Have changes in normal bleeding pattern
Have family history of endometrial cancer
Have abnormal bleeding between the periods
Have bleeding during or after sexual intercourse
Have premenstrual pain or lower abdominal pain
Have bleeding after menopause
Have obstruction of the urinary tract
Are at a risk for the formation of a blood clot
Are diabetic
Are overweight
Have polycystic ovary syndrome (PCOS)

Use in pediatrics:

Safety and effectiveness of TRAKLOT 500 TABLET in children and adolescents below 18 years of age has not been established yet. Consult your child’s doctor for advice. 

Use ineriatrics:

TRAKLOT 500 TABLET is not recommended for use in elderly women after menopause (stoppage of periods). Consult your doctor before taking TRAKLOT 500 TABLET.

INTERACTIONS

A. Drug-Drug interactions:

Before taking TRAKLOT 500 TABLET inform your doctor if you are taking any of the following medicines:

Ethinyl estradiol, levonorgestrel (oral contraceptives used to prevent pregnancy)
Estrogen (used to treat hormone disorder)
Streptokinase, reteplase, tenecteplase (used to a breakdown blood clots)
Tamoxifen (used to treat breast cancer)
Trans-retinoic acid (used to treat acne)
Factor IX complex concentrates (used to stop bleeding)

Overdosage:

If you or anyone else accidentally takes too much of TRAKLOT 500 TABLET, contact your doctor immediately or visit a nearby hospital immediately. Overdosage symptoms of TRAKLOT 500 TABLET are headache, nausea, vomiting, diarrhea, abnormal blood pressure, impaired vision, abnormal mental status, skin rashes, dizziness and fits or seizures.

SYNOPSIS
Drug :  

Tranexamic Acid

Pharmacological Category :  

Antifibrinolytics

Therapeutic Indication :  

Prevent and treats bleeding in various conditions

Dosage Forms :  

Tablet,el, Injection

MORE INFORMATION
Keep out of reach from children
Store at room temperature
FAQs ABOUT TRAKLOT 500 TABLET

Is TRAKLOT 500 TABLET safe for use in patients with impaired kidney function?

TRAKLOT 500 TABLET is not recommended for use in patients with severe kidney impairment.  TRAKLOT 500 TABLET should be used with caution in patients with mild to moderate kidney impairment and your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking TRAKLOT 500 TABLET.

Does TRAKLOT 500 TABLET cause loose stools?

TRAKLOT 500 TABLET can cause side effects such as loose stools. To manage this effect, drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptomets worse.

Is TRAKLOT 500 TABLET used for heavy menstrual bleeding?

TRAKLOT 500 TABLET is used only when your periods are regular to control heavy menstrual bleeding. It reduces the amount of blood lost during your period but may not help other symptoms such as period pain. Do not take this medicine if your periods are not heavy. Consult your doctor before taking TRAKLOT 500 TABLET.

What are the common side effects of TRAKLOT 500 TABLET?

The most common side effects of taking TRAKLOT 500 TABLET are nausea, vomiting, diarrhea, headache, tiredness, muscle cramps, migraine, anemia (lack of red blood cells), stomach pain, sinus and nasal symptoms. Consult your doctor immediately if any of the side effect worsens.     

Can TRAKLOT 500 TABLET be used in pregnant women?

TRAKLOT 500 TABLET should be used with caution in pregnant women only if clearly advised by the doctor. Inform your doctor immediately if you become pregnant or think you may be pregnant before taking TRAKLOT 500 TABLET. 

REFERENCES

1. KD. Tripathi. Drugs affecting blood and blood formation. Essentials of medical pharmacology. 8th Edition. 2019. Page – 676.

2. John M. Chauncey, Jerald S. Wieters. Tranexamic Acid. NIH National Library of Medicine, National center for biotechnology information. [Revised in January 2022] [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK532909/

3. Johnny Cai, Jessica Ribkoff, Sven Olson, Vikram Raghunathan, Hanny Al-Samkari, Thomas. DeLoughery, and Joseph J. Shatzel. The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. 2019 [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023891/

4. Amring Pharmaceuticals, Inc. Tranexamic Acid. NIH National Library of Medicine, DailyMed. [Revised in December 2020] [Accessed on 14th July 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=031bf7c2-3b07-469d-bc5a-31fc6238e25f&type=display#section-9

5. Mercury pharma. Medsafe. Tranexamic acid film-coated tablets 500 mg. [Revised in September 2021] [Accessed on 14th July 2022] https://www.medsafe.govt.nz/profs/datasheet/t/tranexamicacidtab.pdf

6. Taj life sciences Pvt. Ltd. Tranexamic Acid Tablets BP. 250 mg. [Accessed on 14th July 2022] https://tajlifesciences.com/portfolio/tranexamic-acid-tablets-bp-250mg/

7. Taj life sciences Pvt. Ltd. Tranexamic Acid Tablets BP. 500 mg. [Accessed on 14th July 2022] https://tajlifesciesnces.com/portfolio/tranexamic-acid-tablets-bp-500mg/

8. Taj life sciences Pvt. Ltd. Tranexamic Acid Tablets BP. 750 mg. [Accessed on 14th July 2022] https://tajlifesciences.com/portfolio/tranexamic-acid-tablets-bp-750mg/

USEFUL DIAGNOSTIC TESTS
Complete blood count
Kidney function test
Bleeding time/clotting time
Urine analysis
PRODUCT DETAILS
Country Of Origin
India