Rapilif D 8 New Capsule 10’S

US$29.00US$42.00 (-31%)

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INTRODUCTION

RAPILIF D 8 NEW is a combination of Silodosin and Dutasteride which belongs to the group of medicines called Alpha-1 blockers and 5-Alpha reductase inhibitors respectively. RAPILIF D 8 NEW is used to treat signs and symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate to improve symptoms and reduces the risk of acute urinary retention (complete blockage of urine flow) or the need for BPH-related surgery. Benign prostatic hyperplasia (BPH) is a condition when an enlarged prostate gland causes uncomfortable urinary symptoms, such as blocking the flow of urine out of the bladder.

Silodosin is an alpha-1 blocker which helps to improve the flow of urination by relaxing the smooth muscles of bladder and prostrate. Dutasteride is a 5-alpha reductase inhibitor that reduces the production of a stress hormone called dihydrotestosterone which is responsible for causing prostate enlargement by inhibiting the activity of an intracellular enzyme called 5-alpha reductase. Collectively they shrink the size of an enlarged prostate and improve the flow of urine as well as the symptoms of BPH in men.

Before taking RAPILIF D 8 NEW inform your doctor if you have low blood pressure, or liver, kidney, or heart disease as a precaution. Women who are pregnant or can become pregnant should not handle the leaked medicine as it may cause serious harm to the baby. Men being treated with RAPILIF D 8 NEW should not donate blood for at least 6 months after their last dose, in order to prevent the exposure of the medicine to pregnant women via blood transfusion.

Avoid consumption of alcohol while taking RAPILIF D 8 NEW, as it may lower your blood pressure. It is not recommended for use in children and adolescents less than 18 years of age. The most common side effects of taking RAPILIF D 8 NEW are orgasm with reduced or no semen, trouble getting or keeping an erection (impotence), decrease in sex drive (libido), ejaculation problems enlarged or painful breasts, dizziness, low blood pressure while standing up from sitting or lying position. Contact your doctor if any of the symptoms worsen.

USES OF RAPILIF D 8 NEW
To treat signs and symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate
HOW RAPILIF D 8 NEW WORKS

RAPILIF D 8 NEW effectively reduces the symptoms of BPH, where silodosin acts by relaxing the muscles surrounding the bladder and prostate by inhibiting the alpha-1 adrenergic receptors of the lower urinary tract and dutasteride works by inhibiting the activity of an enzyme called 5-alpha reductase, which is responsible for the conversion of testosterone into dihydrotestosterone (a stress hormone that causes BPH). As a result, RAPILIF D 8 NEW help in shrinkage of an enlarged prostate, making it easier for the urine to pass through and provide relief from symptomatic BPH.

DIRECTIONS FOR USE

Take RAPILIF D 8 NEW as advised by your physician. Swallow RAPILIF D 8 NEW with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age and severity of the condition.

SIDE EFFECTS OF RAPILIF D 8 NEW
COMMON
Orgasm with reduced or no semen
Trouble getting or keeping an erection (impotence)
Decrease in sex drive (libido)
Ejaculation problems
Enlarged or painful breasts
Dizziness
Diarrhea
Nasal congestion
Low blood pressure while standing up from sitting or lying position
UNCOMMON
Increased heart rate
Nausea, dry mouth
Skin rash, itching, drug eruption
Low blood pressure
Hair loss or hair growth
RARE
Fainting or loss of consciousness
Fast or irregular heartbeat (irregular heartbeat)

Stop taking RAPILIF D 8 NEW and contact your doctor immediately if you experience any of the following side effects:

Signs of allergic reactions (such as swelling of the eyelids, face or throat, difficulty in breathing, feeling faint, itchy skin or hives, arms, or legs)
Serious skin reactions such as skin peeling
HOW TO MANAGE SIDE EFFECTS

Nausea:

Try to take RAPILIF D 8 NEW with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.

Diarrhea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

Skin rash:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if the symptom did not improve.

Dry mouth:

Try to drink plenty of cold water. Sip on cold unsweetened drinks and use lip balm if your lips are dry. Try to brush your teeth twice a day and use mouthwash. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS
PREGNANCY

RAPILIF D 8 NEW is not recommended for use in women, only used in adult men. Women who are pregnant or can become pregnant should not handle the leaked medicine as it may cause serious harm to the baby. The contact area should be washed immediately with soap and water.

BREASTFEEDING

RAPILIF D 8 NEW is not recommended for use in women, only used in adult men.

DRIVING AND USING MACHINES

Do not drive or handle any machines if you experience low blood pressure when standing up from sitting or lying position (with or without symptoms such as dizziness). Consult your doctor before taking RAPILIF D 8 NEW.

ALCOHOL

Consumption of alcohol is not recommended while taking RAPILIF D 8 NEW, as it may lower your blood pressure.

KIDNEY

RAPILIF D 8 NEW is not recommended for use in patients with severe kidney impairment and it should be used with caution in patients with moderate kidney impairment. Consult your doctor before taking RAPILIF D 8 NEW.

LIVER

RAPILIF D 8 NEW is not recommended for use in patients with severe liver impairment and it should be used with caution in patients with liver problems. Consult your doctor before taking RAPILIF D 8 NEW.

ALLERGY

Do not take RAPILIF D 8 NEW if you are allergic (hypersensitive) to Silodosin or Dutasteride or other 5 alpha-reductase inhibitors such as finasteride.

OTHERS

Before taking RAPILIF D 8 NEW, inform your physician if you:

Have low blood pressure
Planned for cataract surgery or other procedures involving the eyes

Use in pediatrics:

RAPILIF D 8 NEW is not recommended for use in children and adolescents (below 18 years of age) due to lack of safety and effectiveness.

Use in geriatrics:

RAPILIF D 8 NEW should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking RAPILIF D 8 NEW.

INTERACTIONS

A. Drug-Drug interactions:

Before taking RAPILIF D 8 NEW inform to your doctor, if you are taking any of these medicines:

Diltiazem, verapamil, and alpha-blockers such as doxazosin, prazosin (treats high blood pressure)
Ketoconazole, itraconazole (treats fungal infections)
Ritonavir (treats HIV infection)
Troleandomycin, ciprofloxacin, clarithromycin, erythromycin (treats bacterial infection)
Cyclosporine (used to prevent organ rejection after transplant)
Digoxin (treats heart problems)

Overdosage:

If you or anyone else accidentally take too much of RAPILIF D 8 NEW, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of RAPILIF D 8 NEW include low blood pressure.

SYNOPSIS
Drug :   Silodosin and Dutasteride
Pharmacological Category :   Alpha-blockers and 5-alpha-reductase inhibitor
Therapeutic Indication :   Benign prostatic hyperplasia
Dosage Forms :   Tablet, Capsule
MORE INFORMATION
Keep RAPILIF D 8 NEW out of reach of children
Store at room temperature
FAQs ABOUT RAPILIF D 8 NEW

Can RAPILIF D 8 NEW cause infertility?

RAPILIF D 8 NEW can cause sexual impotence, decreased sex drive or difficulty in ejaculation in men because it reduces the sperm count, semen volume and sperm movement. Consult your doctor if this bothers you.

Can the use of RAPILIF D 8 NEW make me feel dizzy?

Yes. RAPILIF D 8 NEW can cause dizziness in some people. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Avoid consumption of alcohol as it can aggravate your dizziness. However, if you experience severe persistent dizziness and fainting while standing up, please contact your doctor.

What to do If I forget to take RAPILIF D 8 NEW?

You should take RAPILIF D 8 NEW immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.

Is RAPILIF D 8 NEW safe to use in children?

RAPILIF D 8 NEW is not recommended for use in children and adolescents (below 18 years). If your child experiences any symptoms of difficulty in urination consult child’s doctor immediately.

Can I take RAPILIF D 8 NEW with blood pressure medicine?

No, before taking RAPILIF D 8 NEW inform your doctor about your previous medication history. This medicine can interact with blood pressure medicines (e.g., prazosin, furosemide) resulting in severe decrease in blood pressure and may cause dizziness or fainting.

REFERENCES

1. KD. Tripathi. Antiadrenergic Drugs and Drugs for Glaucoma & Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 142-144 & 303.

2. Kazuhisa Hagiwara, Takuya Koie, Hiromichi Iwamura, Atsushi Imai, Shingo Hatakeyama, Takahiro Yoneyama, Yasuhiro Hashimoto and Chikara Ohyama. Efficacy and Safety of Silodosin and Dutasteride Combination Therapy in Acute Urinary Retention due to Benign Prostatic Hyperplasia: A Single-Arm Prospective Study. April 2016. [Accessed on 25th August 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852328/

3. Iram Kahkashan, Shabnam Chawdhary, Vishal R. Tandon, Rahul Gupta. To compare the efficacy and safety of silodosin and dutasteride combination with alfuzosin and dutasteride combination in patients of benign prostatic hyperplasia: a randomized, open label study. International journal of basic & clinical pharmacology (IJBCP). 2019. [Accessed on 25th August 2021] https://www.ijbcp.com/index.php/ijbcp/article/view/3207

4. Cipla House. Swiss Garnier Genexiaa Sciences Pvt. Ltd. [Revised in February 2021] [Accessed on 25th August 2021] https://www.ciplamed.com/print-product-pdf/49744

5. APL Swift Services (Malta) Limited or Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in August 2019] [Accessed on 25th August 2021]. https://www.medicines.org.uk/emc/files/pil.9277.pdf

6. Recordati S.p.A. European Medicines Agency (EMA). [Accessed on 25th August 2021] https://www.ema.europa.eu/en/documents/product-information/silodyx-epar-product-information_en.pdf

VIDEOS
Dutasteride+Silodosin CAPSULE – Drug Information

Dutasteride+Silodosin CAPSULE : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

PRODUCT DETAILS
Net Qty
1 N
Shelf Life
24 months
Item Weight
17.5 g
Ingredient
DUTASTERIDE 0.5MG+SILODOSIN 8MG
Hsn Code
30049099
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Rapilif D 8 New Capsule 10'S

US$29.00US$42.00 (-31%)

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