NERSAVE A Tablet 10’s

INTRODUCTION

NERSAVE A TABLET is a combination of Aceclofenac and Pregabalin which belongs to the group of medicines called Analgesics and Anticonvulsants respectively. It is used to treat nerve pain (also known as neuropathic pain).

It can also be used to provide relief from joint pain (Ex. osteoarthritis, rheumatoid arthritis), back pain (Ex. ankylosing spondylitis), neck pain, sciatic nerve pain (pain from the nerve that runs at the back of the legs) and pain caused due to injuries or surgeries.

NERSAVE A TABLET is preferably taken with or after meals to avoid gastric irritation. Avoid smoking or consumption of alcohol as it could aggravate the risk of stomach problems. Do not take NERSAVE A TABLET if you have any ulcers, bleeding or perforations in the gut.

Before taking NERSAVE A TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have diabetes, hypertension, high blood cholesterol, any inflammation in the bowel or intestines, blood clots, bleeding problems or a previous history of stomach ulcers as a precaution. NERSAVE A TABLET is not recommended for use in pregnant or breastfeeding women.

The most common side effects of taking NERSAVE A TABLET are nausea, indigestion, heartburn, stomach pain, constipation, dizziness, drowsiness, headache, lack of attention, clumsiness, memory impairment, tingling or numbness, blurred vision, weight gain, difficulties with erection, decreased sexual drive, delayed ejaculation and muscle cramps. Consult your doctor if any of these side effect worsens.

USES OF NERSAVE A TABLET

It is used to treat:

Nerve pain
Joint pain (Ex. osteoarthritis, rheumatoid arthritis)
Back pain (Ex. ankylosing spondylitis)
Neck pain
Sciatic nerve pain (pain from the nerve that runs at the back of the legs)
Post-surgical/injury pain
HOW NERSAVE A TABLET WORKS

NERSAVE A TABLET is a pain-relieving medicine. It reduces pain sensation by interfering with the pain signals travelling between the damaged nerves and the brain. It also blocks the release of certain chemicals (such as prostaglandins) in the body that causes pain, inflammation and swelling. As a result, it reduces nerve pain, joint pain and back pain.

DIRECTIONS FOR USE

Take NERSAVE A TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It is preferably taken with meals to avoid gastric irritation.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF NERSAVE A TABLET
COMMON
Dizziness, drowsiness, headache
Increased appetite
Increased mood, confusion, disorientation, irritability
Lack of attention, clumsiness, memory impairment
Tremor, difficulty in speaking
Tingling or numbness, sedation, lethargy
Difficulty in sleeping, tiredness
Blurred vision, double vision
Spinning sensation, problems with balance
Dry mouth, constipation, vomiting, flatulence, diarrhea, nausea, swelling in abdomen
Swelling of the extremities (such as hands, legs or fingers)
Feeling drunk, abnormal style of walking
Weight gain
Muscle cramps, joint or back pain, pain in limbs
Sore throat
Difficulties with erection, decreased sexual drive, delayed ejaculation
UNCOMMON
Loss of appetite, weight loss, flatulence
High or low blood sugar
Hallucinations, mood changes
Mouth ulcers
Dry eyes, eye pain, watery eyes, eye swelling
Heart rate disturbances, high or low blood pressure
Flushing
Difficulty in breathing, dry nose, nasal congestion
Increased salivation, heartburn, numbness around mouth
Sweating, rash, chills, fever
Breast pain
Difficulty or painful urination
Allergic reaction (swollen face, itchiness, hives, runny nose, nose bleeding)
Painful menstruation
Cold hands and feet
Increase in blood urea levels
Increase in blood creatinine levels
RARE
Abnormal sense of smell
Cold sweat, tightness of the throat, swelling of tongue
Inflammation of the pancreas
Difficulty with writing properly
Fluid in the lungs
Muscle damage
Discharge from breasts, abnormal growth of breast in men
Low urine output
Signs of Parkinsonism (muscle stiffness, shaking and decreased ability to move)
Anemia

Stop taking NERSAVE A TABLET and consult your doctor immediately if you experience any of the following:

Signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing, chest tightness, fever, ulcers on the mucous membrane, oral sores)
Severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane, joint pain with fever)
Signs of brain inflammation (such as high fever, headache, vomiting, blotchy red rashes, neck stiffness, sensitivity and intolerance to light)
Bloody stools, vomits or urine
Heart attack or stroke
Difficulty in passing urine, painful urination, low urine output
Severe stomach pain with indigestion and heartburn
Signs of low blood count (causing tiredness, breathlessness, joint pain, repeated infections, increased bleeding and bruising)
Low potassium levels in blood causing blood vessel inflammation
Fall or accidental injury
Blurred vision or vision changes
Fits (convulsions)
Suicidal thoughts or thoughts of harming or killing themselves
HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take NERSAVE A TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if the symptom did not improve.

Mouth ulcers:

Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on the affected areas of the mouth if required. Consult your doctor if the symptom did not improve.

Diarrhea

Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.

Skin rash:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.

WARNING & PRECAUTIONS
PREGNANCY

NERSAVE A TABLET is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it. Women of childbearing age must use a suitable contraceptive method (non-hormonal methods) to avoid pregnancy while undergoing therapy with NERSAVE A TABLET.

BREASTFEEDING

NERSAVE A TABLET is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking NERSAVE A TABLET.

ALCOHOL

Avoid consumption of alcohol while taking NERSAVE A TABLET as it could make you feel dizzier and drowsier.

KIDNEY

NERSAVE A TABLET is not recommended for use in patients with moderate to severe kidney diseases. It should be used with caution in patients with other mild kidney problems. Therefore, consult your doctor before taking it.

LIVER

NERSAVE A TABLET is not recommended in patients with severe liver problems (such as liver failure). It should be used with caution in patients with other mild liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take NERSAVE A TABLET if you are allergic to Pregabalin, Aceclofenac or to any other NSAIDs (such as aspirin, ibuprofen, naproxen or diclofenac).

LUNGS

NERSAVE A TABLET is not recommended for use in patients who previous experienced asthma attack or breathing difficulties after taking any pain-relieving medicine. It should be used with caution in patients with asthma or any other breathing problems. Therefore, consult your doctor before taking it.

HEART DISEASE

NERSAVE A TABLET is not recommended for use in patients with severe heart problems (such as heart attack). It should be used with caution in patients with other heart problems (such as angina). Therefore, consult your doctor before taking it.

OTHERS

NERSAVE A TABLET is not recommended for use if you:

Have GI bleeding (bloody stools or vomits)
Have ulcers in the stomach or intestines
Have stroke or any problems in blood circulation
Have bleeding or any blood clotting disorders
Recently had an operation to clear or bypass blockages

Before taking NERSAVE A TABLET inform your doctor if you:

Have porphyria
Have diabetes
Have high blood pressure
Have blood cholesterol levels
Have inflammation of the bowel (Ex. Ulcerative colitis, Crohn’s Disease)
Have holes or blockage in the gut
Have a history of stomach ulcers
Have any autoimmune disorders that affects the skin (Systemic lupus erythematosus)
Smoke
Are an alcoholic
Have a habit of drug abuse or dependence
Have blood clots in the body
Recently had any surgery
Have chickenpox

Use in Pediatrics:

NERSAVE A TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.

Use in Geriatrics:

NERSAVE A TABLET should be used with caution in elderly patients. Therefore, consult your doctor for advice before taking it.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking NERSAVE A TABLET, inform your doctor if you are taking any of the following medicines such as:

Other medicines used to treat pain (Ex. aspirin, ibuprofen, naproxen, celecoxib, etoricoxib)
Medicines used to treat increased blood pressure (Ex. enalapril, lisinopril, losartan, candesartan, methyldopa, clonidine, propranolol)
Diuretics (used to reduce edema and blood pressure) Ex. furosemide, hydrochlorothiazide
Cardiac glycosides (used to correct heart rhythm (Ex. digoxin)
Medicines used to suppress immune system after organ transplantation (Ex. ciclosporin or tacrolimus)
Medicines used to stop blood clotting (Ex. warfarin, heparin, clopidogrel)
Corticosteroids (used to treat pain and inflammation) Ex. hydrocortisone, prednisolone
Medicines used to treat infections (Ex. ciprofloxacin, ofloxacin, levofloxacin, moxifloxacin)
Medicines used to treat depression (Ex. citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine and sertraline)
Medicines used to treat cancer and autoimmune disorders such as arthritis and skin conditions (Ex. methotrexate)
Mifepristone, ethinyl estradiol (birth control pills)
Medicines used to treat HIV infection (Ex. zidovudine)
Medicines used to treat diabetes (Ex. glibenclamide, gliclazide, tolbutamide)
Oxycodone (used as a pain killer)
Lorazepam (used for reducing anxiety)
Opioid analgesics (used for pain relief) such as morphine, pethidine, fentanyl
Medicines used to reduce muscle pain or spasms (baclofen, tizanidine, chlorzoxazone)

Overdosage:

If you or anyone else accidentally took more NERSAVE A TABLET, consult your doctor immediately or visit the nearby hospital straight away. Symptoms of overdosage might include sleepiness, confusion, agitation, restlessness and fits.

SYNOPSIS
Drug :   Aceclofenac, Pregabalin
Pharmacological Category :   COX-2 inhibitor, GABA Analogs
Therapeutic Indication :   Pain Relief
Dosage Forms :   Tablet
MORE INFORMATION
Keep NERSAVE A TABLET out of reach of children
Store NERSAVE A TABLET at room temperature
Protect from light and moisture
FAQs ABOUT NERSAVE A TABLET

Q: How long will it take for NERSAVE A TABLET to start acting?

A: NERSAVE A TABLET may start to exert its analgesic effects from day 2 of administration. An initial benefit of pain relief can be seen in patients after 2-4 weeks of therapy. However, it may take few months to show effects in some individuals.

Q: Can NERSAVE A TABLET treat diabetic neuropathy?

A: Yes. NERSAVE A TABLET can be used to treat diabetic neuropathy. It provides symptomatic pain relief in patients who have nerve pain caused due to diabetes.

Q: What happens if I stop taking NERSAVE A TABLET?

A: Do not stop taking NERSAVE A TABLET unless your doctor tells you as it may lead to withdrawal symptoms such as difficulty in falling asleep, anxiety, nausea, headache, diarrhea, flu-like symptoms, fits, nervousness, depression, dizziness, pain and sweating. Therefore, continue to take NERSAVE A TABLET as long as instructed by your doctor to achieve better results.

Q: Is taking NERSAVE A TABLET safe?

A: The safety of NERSAVE A TABLET varies with patient to patient. Your doctor will closely monitor your health condition while taking NERSAVE A TABLET to avoid the risk of side effects.

Q: Is NERSAVE A TABLET addictive?

A: Research has shown that NERSAVE A TABLET can cause drug abuse or dependence. Therefore, it is better to inform your doctor before taking this medicine, if you already have a previous history of substance abuse as a precaution.

Q: Can NERSAVE A TABLET cause weight gain? If so, how can I manage my weight?

A: NERSAVE A TABLET may increase your body weight. It increases your hunger (appetite) which makes you eat more and eventually leads to increase in body weight. Weight can be managed by doing regular exercise and by eating a healthy balanced diet. Avoid calorie-rich foods such as soft drinks, chips, cakes, biscuits and sweets. Research says that patients with diabetes tend to put on weight easily while taking NERSAVE A TABLET. Dose adjustments for antidiabetic medicines can help in such situations. If the symptom bothers you, consult your doctor for advice.

Q: Can NERSAVE A TABLET cause sleepiness or drowsiness?

A: Yes. NERSAVE A TABLET may cause sleepiness and drowsiness. Rest and relax while feeling sleepy. Avoid consumption of alcohol while taking NERSAVE A TABLET as it can make you feel drowsier. Do not drive or operate any tools or machines while you are feeling sleepy. Consult your doctor if the symptom bothers you.

Q: Will the use of NERSAVE A TABLET affect my sex life?

A: Yes. NERSAVE A TABLET can affect sexual life of both men and women. It decreases sexual desire in men and women and can cause difficulty in erection or delayed ejaculation in men. The exact mechanism behind these effects is not known. If you experience any such problems, contact your doctor immediately.

Q: Can I take NERSAVE A TABLET along with alcohol?

A: No. Avoid consumption of alcohol while taking NERSAVE A TABLET as it may make you feel drowsier. Moreover, NERSAVE A TABLET is not recommended for use in patients having alcohol abuse unless considered necessary. Therefore, consult your doctor before taking it.

Q: Can I take a higher dose of NERSAVE A TABLET to increase pain relieving effects?

A: No. Do not take a higher dose of NERSAVE A TABLET than recommended by your doctor. Taking a higher dose of NERSAVE A TABLET without consulting a doctor can increase the risk of toxicity and can lead to side effects. If the prescribed dose is not effective for you, consult your doctor for a suitable higher dose. Never consume a higher dose NERSAVE A TABLET without proper medical supervision.

Q: What to do if I forgot to take NERSAVE A TABLET?

A: Take NERSAVE A TABLET as soon as you remember until it’s time for the next one. If you missed a dose, skip the missed one and take the next dose at time normally you would take. Do not take a double dose to make up the missed one, as it may lead to overdosage. If you are not sure, consult your doctor. Your doctor may instruct you about the next steps.

Q: What are the precautions that I need to follow while taking NERSAVE A TABLET?

A: Before taking NERSAVE A TABLET, inform your doctor about your pre-existing disease conditions (such as liver problems, kidney problems, stomach problems) as a precaution. NERSAVE A TABLET should not be used if you are planning to become pregnant without consulting your doctor. NERSAVE A TABLET can cause extreme sleepiness and dizziness and therefore avoid taking other medicines or alcohol that can make you feel drowsier ever more. It can also impair memory, attention and thinking ability in few individuals and so avoid travelling or driving on your own for a while. If case of any queries, consult your doctor for advice.

Q: How to take NERSAVE A TABLET?

A: Take NERSAVE A TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not chew or crush the medicine. It is preferably taken with meals to avoid gastric irritation.

Q: Can I take NERSAVE A TABLET daily?

A: Take NERSAVE A TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take NERSAVE A TABLET every day or not.

Q: Is NERSAVE A TABLET safe to use in diabetic patients?

A: NERSAVE A TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking NERSAVE A TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.

Q: Can the use of NERSAVE A TABLET affect the liver?

A: Yes. NERSAVE A TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is not recommended for use in patients with liver failure. It should be used with caution in patients with other mild liver problems. Consult your doctor before taking it.

Q: How NERSAVE A TABLET works?

A: NERSAVE A TABLET is a pain-relieving medicine. It reduces pain sensation by interfering with the pain signals travelling between the damaged nerves and the brain. It also blocks the release of certain chemicals (such as prostaglandins) in the body that causes pain, inflammation and swelling. As a result, it reduces nerve pain, joint pain and back pain.

Q: What are the side effects of NERSAVE A TABLET?

The most common side effects of taking NERSAVE A TABLET are nausea, indigestion, heartburn, stomach pain, constipation, dizziness, drowsiness, headache, lack of attention, clumsiness, memory impairment, tingling or numbness, blurred vision, weight gain, difficulties with erection, decreased sexual drive, delayed ejaculation and muscle cramps. Consult your doctor if any of these side effect worsens.

REFERENCES

1. KD. Tripathi. Nonsteroidal Anti-Inflammatory Drugs and Antipyretic-Analgesics. Antiepileptic Drugs. Essentials of Medical Pharmacology. Seventh edition. Page – 204 & 790.

2. K. Yashas Sree, B Mounica, L Chandini Devi, K Divya Vani, Dr. M Pratibha, Dr. M Sudhakar. A study on efficacy of aceclofenac versus aceclofenac plus pregabalin in management of nonspecific chronic low back pain. International Journal of Medical and Health Research. 2019. [Accessed on 14th January 2023]. http://www.medicalsciencejournal.com/archives/2019/vol5/issue6/5-6-11

3. Laboratories BTT. Aceclofenac 100 mg Film-coated Tablets Aceclofenac. Electronic Medicines Compendium. [Revised in January 2016]. [Accessed on 14th January 2023]. https://www.medicines.org.uk/emc/files/pil.2389.pdf

4. MSN Laboratories Europe Limited. Pregabalin. Electronic Medicines Compendium. [Revised in March 2022]. [Accessed on 14th January 2023]. https://www.medicines.org.uk/emc/files/pil.13402.pdf

5. Lyrica (Pregabalin). Frequently asked questions. [Accessed on 14th January 2023]. https://www.lyrica.com/frequently-asked-questions

6. Leeford Healthcare Pvt Ltd. Alcinac PG Forte. [Accessed on 14th January 2023]. https://www.leeford.in/product/870/alcinac-pg-forte

USEFUL DIAGNOSTIC TESTS
Nerve conduction test
Electroencephalogram (EEG)
Net Qty
1 N
Item Weight
17.5 g
Ingredient
ACECLOFENAC 200 mg+PREGABALIN 75 mg
Hsn Code
30049069
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