ACOLATE M Tablet 10’s

INTRODUCTION

ACOLATE M TABLET is a combination of Levocetirizine and Montelukast which belongs to the group of medicines called H1 receptor antagonists and Leukotriene receptor antagonists respectively. ACOLATE M TABLET is indicated for the treatment and prevention of allergic rhinitis, chronic idiopathic urticaria (allergic skin reaction with red raised itchy bumps on skin) and bronchial asthma in adults and in adolescents (aged 15 years or above).  

Allergic rhinitis (also known as hay fever) is a heterogeneous disorder characterized by inflammation of the inner lining of nose accompanied by nasal decongestion, repeated sneezing, wheezing, or a red, watery and itchy eyes.  

It is usually caused by allergens such as pollens, dusts, mould or flakes of skin from certain animals and can occur seasonally or year-round. Bronchial asthma is a long-term medical condition in which the path of the airways becomes inflamed, narrow and swollen. Symptoms include coughing, wheezing and chest tightness.

ACOLATE M TABLET is contraindicated for use in patients having severe kidney impairment. Consult your doctor before use. Avoid consumption of alcohol while taking ACOLATE M TABLET as it could make you feel drowsier.  

ACOLATE M TABLET may cause certain unpleasant neuropsychiatric events (such as anxiety, depression, nightmares, hallucinations or even suicidal thoughts) in some individuals. Contact your doctor immediately if you or anyone else experience such events during treatment with ACOLATE M TABLET.  

The most common side effects of taking ACOLATE M TABLET are upper respiratory tract infection, fever, cough, inflammation of the pharynx, dryness of mouth, headache and sleepiness. Consult your doctor if any of the side effects worsen.

USES OF ACOLATE M TABLET
Treats and prevents allergic rhinitis, chronic idiopathic urticaria and bronchial asthma in adults and in adolescents (aged 15 years or above)
HOW ACOLATE M TABLET WORKS

ACOLATE M TABLET provides relief from the symptoms of allergic rhinitis, asthma and urticaria where levocetirizine acts by blocking the actions of histamines (a substance that cause allergic reaction), at the H1 receptors present on the surface of cells and montelukast acts by blocking the action of leukotrienes D4 (an inflammatory molecule causing narrowing and swelling of the airways) in the lungs, thus causing relaxation of smooth muscle, reduction in swelling and/or inflammation of the airways and a marked decrease in the onset of allergic reactions.

DIRECTIONS FOR USE

Take ACOLATE M TABLET as advised by your physician. Swallow ACOLATE M TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of ACOLATE M TABLET for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF ACOLATE M TABLET
COMMON
Upper respiratory infection
Cough, cold, fever or flu-like symptoms
Pharyngitis (inflammation of the pharynx)
Headache and tiredness
Dizziness, sleepiness
Nausea, vomiting, dry mouth, thirst, stomach pain, diarrhoea, indigestion
Otitis media (inflammation or infection of the ears)
Skin rash
Bleeding from the nose
Muscle pain, joint pain
UNCOMMON
Exhaustion
Behaviour and mood-related changes
Agitation including aggressive behaviour or hostility
Seizures
Dream abnormalities
Restlessness
Drowsiness
Bruising, itching, hives
Muscle pain, muscle cramps, weakness
Feeling unwell, swelling
RARE
Increased bleeding tendency
Uncontrolled muscle movements
Angioedema (swelling underneath the skin)
Palpitations (fast heartbeat)

Stop giving ACOLATE M TABLET to your child and contact doctor immediately if your child experiences any of the following side effects:  

Severe allergic reactions (such as skin rash, itching, swelling of the face, eyelids, mouth, throat and neck and difficulty in breathing or swallowing)
Systemic eosinophilia (increased levels of WBC in the blood)
Vasculitis or Churg-Strauss syndrome (inflammation of the blood vessels)
Neuropsychiatric disorders (such as agitation, anxiety, depression, disorientation, hyperactivity, nightmares, hallucinations, insomnia, memory impairment, walking in sleep, tremor, attention disturbance)
Thoughts of harming or killing yourself (suicidal ideation)
HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Try to take ACOLATE M TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.

Diarrhoea:

Drink lots of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own to treat diarrhoea. Consult your doctor if the symptom did not improve.

Headache:  

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve.

WARNING & PRECAUTIONS
PREGNANCY

ACOLATE M TABLET should be used with caution during pregnancy only if considered clearly necessary. Consult your doctor before taking ACOLATE M TABLET.    

BREASTFEEDING

ACOLATE M TABLET should be used with caution in breast-feeding. Consult your doctor before taking ACOLATE M TABLET.   

DRIVING AND USING MACHINES

Do not drive or operate any machines if you experience sleepiness/drowsiness, fatigue or physical weakness. Consult your doctor before taking ACOLATE M TABLET.   

ALCOHOL

Avoid consumption of alcohol while taking ACOLATE M TABLET as it could cause a reduction in alertness and impairment of performance. Consult your doctor before taking ACOLATE M TABLET.  

KIDNEY

ACOLATE M TABLET is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease. Consult your doctor before taking ACOLATE M TABLET.  

LUNGS

ACOLATE M TABLET is not recommended for use in patients with asthma attacks. Consult your doctor before taking ACOLATE M TABLET. 

OTHERS

ACOLATE M TABLET is not recommended for use if you:

Have galactose intolerance (inherited condition in which the body cannot convert galactose to glucose)
Have Lapp lactase deficiency (deficiency of the enzyme lactase in the body)
Have glucose-galactose malabsorption
Have phenylketonuria (release of phenylalanine in urine)

Before taking ACOLATE M TABLET, inform your physician if you:

Have or at risk of having epilepsy
Have scheduled allergy skin tests
Have sensitivity to aspirin or other NSAIDs
Have any predisposing factors of urinary retention (Ex. spinal cord lesion, prostatic hyperplasia)

Use in pediatrics:

ACOLATE M TABLET is strictly not recommended for use in infants and children (aged below 15 years). Consult your child’s doctor for advice.

Use in geriatrics:

ACOLATE M TABLET should be used with caution in elderly patients (aged 65 years or above). Proper dose titrations and careful monitoring of kidney functions are required in such patients. Consult your doctor before taking ACOLATE M TABLET.

INTERACTIONS

A. Drug-Drug interactions:

Before taking ACOLATE M TABLET, inform your doctor, if you are taking any of the following medicines:

Gemfibrozil (used to control high blood cholesterol levels)
CNS depressants (Ex. phenobarbital), phenytoin (used to treat epilepsy)
Rifampicin (used to treat tuberculosis)
Ritonavir (a medicine used to treat viral infections)
Theophylline (a medicine used to treat asthma)

Overdosage:

If you or anyone else take too much of ACOLATE M TABLET, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of ACOLATE M TABLET might include stomach pain, thirst, sleepiness, headache, vomiting, hyperactivity, agitation, excitation and restlessness.

SYNOPSIS
Drug :   Levocetirizine, Montelukast
Pharmacological Category :   H1 receptor antagonist, Leukotriene receptor antagonist
Therapeutic Indication :   Allergic rhinitis, Bronchial asthma, Chronic idiopathic urticaria
Dosage Forms :   Tablet, Capsule, Dispersible Tablet, Oral Solution, Syrup, Suspension
MORE INFORMATION
Keep ACOLATE M TABLET out of reach of children
Store ACOLATE M TABLET at room temperature
FAQs ABOUT ACOLATE M TABLET

How long does it take for ACOLATE M TABLET to provide relief from symptoms?

Following oral administration with ACOLATE M TABLET, it is believed to provide relief from the symptoms of allergy and asthma within 30 minutes to an hour. Please note that the onset of action varies from product to product and consult your doctor if you have any queries.

Can ACOLATE M TABLET be used to treat acute asthma attacks?

No, ACOLATE M TABLET is used only to prevent asthma attacks. ACOLATE M TABLET should not be used on an asthma attack that has been started already. Contact your doctor or go to the nearby hospital to avoid exacerbation of the attack.   

Can ACOLATE M TABLET be used in infants?

No, ACOLATE M TABLET is only meant to be used in adults and in adolescents (aged 15 years or above). ACOLATE M TABLET is strictly not recommended for use in children aged between 6 months to 11 years of age without consulting your doctor.  

Can ACOLATE M TABLET make you feel sleepy?

Yes, ACOLATE M TABLET may make you feel sleepy or drowsy. Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling sleepy. Avoid alcohol intake, as it could aggravate your existing condition. Consult your doctor if the symptom did not improve.

Is ACOLATE M TABLET safe to use in patients with kidney problems?

ACOLATE M TABLET is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease. Consult your doctor before taking ACOLATE M TABLET. 

REFERENCES

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USEFUL DIAGNOSTIC TESTS
Complete Blood Count
VIDEOS
Levocetirizine Montelukast Tablet – Drug Information

Levocetirizine Montelukast Tablet : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

PRODUCT DETAILS
Country Of Origin
India