AB Phylline Syrup 100ml

INTRODUCTION

AB PHYLLINE contains Acebrophylline which belongs to theroup of medicines called bronchodilators. It is used in the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and bronchitis. Chronic obstructive pulmonary disease (COPD) is a chronic progressive inflammatory lung disease caused by long-term exposure to irritatingases or cigarette smoking, which results in obstructed airflow from lungs. It is characterized by cough, sputum production, wheezing and difficulty in breathing.

Bronchial asthma is a chronic medical condition in which the airway path of the lungs becomes swollen and narrow. Bronchitis is a condition where the lining of bronchial tubes are inflamed as resulting in cough and sputum production. Acebrophylline has bronchodilating, mucolytic and anti-inflammatory properties. It promotes relaxation of bronchial muscles, reduces mucus secretions and inhibits the production of powerful pro-inflammatory cytokines which results in inflammation.

The most common side effects occur during this medication are nausea, vomiting, dizziness, stomach pain, diarrhea, constipation or heart burn. Before taking this medicine, inform your doctor if you have heart, kidney or liver disease. This medicine is not recommended for use in pregnant or breastfeeding women unless prescribed by your physician.

USES OF AB PHYLLINE
Treats chronic obstructive pulmonary disease
Treats bronchial asthma
Treats bronchitis
HOW AB PHYLLINE WORKS

AB PHYLLINE inhibits the secretions of intracellular phosphodiesterases and increase the levels of cyclic-AMP, leading to the relaxation of bronchial muscles and bronchodilation. It acts as a mucolytic by decreasing the viscosity of secretions and by increasing mucociliary clearance. It also inhibits the production of powerful pro-inflammatory substances like leukotrienes and tumor necrosis factor and reduces inflammation in airways.

DIRECTIONS FOR USE

Take AB PHYLLINE as directed by your physician. Shake well before use. Try taking this medicine at the same time each day. Your doctor will decide the correct dose and duration for you depending upon your age, weight and body condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF AB PHYLLINE
SERIOUS
Chills and fever
COMMON
Transient nausea, vomiting
Dizziness or drowsiness
Abdominal distension or pain
Diarrhea, constipation, heart burn
Loss of appetite
Esophageal bleeding
Skin rash or itching
Difficulty in breathing
Nasal inflammation
RARE
Headache
Occasional numbness including numbness in arm
Insomnia (lack of sleep)
Tachycardia (fast heartbeat)
Fatigue (tiredness)
High or low blood pressure
HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Constipation: 

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Skin rash:

Avoid hot showers because hot water can irritate the scalp. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does notet better within a week, speak to a doctor.

WARNING & PRECAUTIONS
PREGNANCY

AB PHYLLINE is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

AB PHYLLINE is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

ALCOHOL

Consumption of alcohol is not recommended during treatment with AB PHYLLINE.

KIDNEY

AB PHYLLINE should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

LIVER

AB PHYLLINE should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to acebrophylline, ambroxol, theophylline or any other xanthine derivatives.

HEART DISEASE

Do not take this medicine if you are suffering from severe heart diseases. Consult your doctor for advice.

INTERACTIONS

Talk to your doctor, if you are taking,

Medicines used to treat infections (e.g. ciprofloxacin, erythromycin, amoxicillin, thiabendazole and doxycycline)
Medicines used to treat heart problems (e.g. diltiazem, verapamil, frusemide, isoprenaline)
Allopurinol (used to treatout)
Cimetidine (used to treat stomach ulcers)
Corticosteroids (used to treat inflammatory disease)
Oral contraceptives (birth control pills)
SYNOPSIS
Drug :   Acebrophylline
Pharmacological Category :   Bronchodilators
Therapeutic Indication :   Chronic obstructive pulmonary disease, bronchial asthma, bronchitis
Dosage Forms :   Tablet, Capsule, Syrup
MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT AB PHYLLINE

Can AB PHYLLINE cause heart problems?

This medicine should be avoided in patients having any heart disease, because it can cause tachycardia and high or low blood pressure in some individuals.

Can AB PHYLLINE be taken during pregnancy?

No. The medicine is not recommended for use during pregnancy. Consult your doctor before taking.

What are the uses of AB PHYLLINE?

It is used to treat chronic obstructive pulmonary disease (COPD), bronchial asthma and bronchitis.

REFERENCES

1. Joshua M.alanter and Homer A. Boushey. Drugs Used in Asthma. Basic & Clinical Pharmacology. Fourteenth Edition. New York McGraw-Hill Education 2018. Page – 352-353.

2. Hyundai Pharmaceutical Co., LTD. Compare Safety and Pharmacokinetic Properties of Surfolase Capsule (Acebrophylline 100mg) and Surfolase CR (200mg). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on March 2015] [Accessed 4th November 2020] https://clinicaltrials.gov/ct2/show/NCT02395913

3. E Pozzi. Acebrophylline: an airway mucoregulator and anti-inflammatory agent. NIH National Library of Medicine, National Center of Biotechnology Information Pubmed.gov. June 2007. [Accessed 4th November 2020] https://pubmed.ncbi.nlm.nih.gov/17695695/

4.iovanniAgliati. Acebrophylline in the treatment of chronic obstructive pulmonary disease. Current Therapeutic Research Volume 56, Issue 2. February 1995. Pages 169-175. [Accessed 4th November 2020] https://www.sciencedirect.com/science/article/pii/0011393X95850422

5. Ciplamed. Respiratory medicine. MUCOPHYLIN Capsules (Acebrophylline). Ciplamed.com [Revised on November 2013] [Accessed 4th November 2020] https://www.ciplamed.com/content/mucophylin-capsules

USEFUL DIAGNOSTIC TESTS
Absolute Eosinophil Count
Complete Blood Count
PRODUCT DETAILS
Net Qty
1 N
Item Weight
120
Ingredient
ACEBROPHYLLINE 50MG
Hsn Code
30049099
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